Publications
Research paper
- I. Marin de Mas, V. A. Selivanov, S. Marin, J. Roca, M. Orešič, L. Agius, M. Cascante, Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions, BMC Syst. Biol. 5, e175 (2011).
- M. Kankainen, P. Gopalacharyulu, L. Holm, M. Orešič, MPEA – metabolite pathway enrichment analysis, Bioinformatics 27, 1878-1879 (2011).
- K. Pietiläinen, T. Róg, T. Seppänen-Laakso, S. Virtue, P. Gopalacharyulu, J. Tang, S. Rodriguez-Cuenca, A. Maciejewski, J. Naukkarinen, A. Rissanen, A.-L.Ruskeepää, P. Niemelä, V. Velagapudi, S. Castillo, H. Nygren, T. Hyötyläinen, J. Kaprio, H. Yki-Järvinen, I. Vattulainen, A. Vidal-Puig, M. Orešič,
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans, PLoS Biol. 9(6), e1000623 (2011). (commentary)
- M. Kankainen, P. Gopalacharyulu, L. Holm, M. Orešič, MPEA-metabolite pathway enrichment analysis, Bioinformatics (2011). doi: 10.1093/bioinformatics/btr278
- H. Nygren, T. Seppänen-Laakso, S. Castillo, T. Hyötyläinen, M. Orešič, Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics for studies of body fluids and tissues, Methods Mol. Biol. 708, 247-257 (2011).
- Gema Alcarraz-Vizán, Joan Boren, Wai-Nang Paul Lee, Marta Cascante, Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation Metabolomics. 2010 June; 6(2): 229-237. (2010)
- T. Pluskal, S. Castillo, A. Villar-Briones, M. Orešič, MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data, BMC Bioinformatics 11, 395 (2010).
- Juan-Carlos Rodríguez-Prados, Paqui G. Través, Jimena Cuenca, Daniel Rico, Julián Aragonés, Paloma Martín-Sanz, Marta Cascante, and Lisardo Boscá, Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation J. Immunol. 2010;185;605-614; doi:10.4049/jimmunol.0901698 (2010)
- Selivanov VA, Votyakova TV, Zeak JA, Trucco M, Roca J, et al. Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia. PLoS Comput Biol 5(12): e1000619. doi:10.1371/journal.pcbi.1000619 (2009).
- T. Pluskal, S. Castillo, A. Villar-Briones, M. Orešič, MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data, BMC Bioinformatics 11, 395 (2010).
- L. Yetukuri, S. Söderlund, A. Koivuniemi, T. Seppänen-Laakso, P. S. Niemelä, M. Hyvönen, M.-R. Taskinen, I. Vattulainen, M. Jauhiainen, M. Orešič, Composition and lipid spatial distribution of High Density Lipoprotein particles in subjects with low and high HDL-cholesterol, J. Lipid Res. 51, 2341-2351 (2010).
- Alcarraz-Vizán G, Boren J, Paul Lee W., Cascante M. Histone deacetylase inhibition results in a common metabolic profile associated with HT29 diferentation. Metabolomics, January 2010; DOI 10.1007/s11306-009-0192-0
- Selivanov VA, Votyakova TV, Zeak JA, Trucco M, Roca J, Cascante M. Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia. Plos Comput Biol. Dec 2009; 5(12): e1000619
- Velagapudi VR, Hezaveh R, Reigstad CS, Gopalacharyulu PV, Yetukuri L, Islam S, Felin J, Perkins R, Boren J, Orešič M, Backhed F. The gut microbiota modulates host energy and lipid metabolism in mice. J Lipid Res. 2009 Dec 29. [Epub ahead of print]
- Touriño S, Fuguet E, Vinardell MP, Cascante M, Torres JL. Phenolic metabolites of grape antioxidant dietary fiber in rat urine. Agric. Food Chem. Nov 2009; 57(23), 11418-26.
- Hiukka A, Ståhlman M, Pettersson C, Levin M, Adiels M, Teneberg S, Leinonen ES, Hultén LM, Wiklund O, Orešič M, Olofsson SO, Taskinen MR, Ekroos K, Borén J. ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan. Diabetes. 2009; 58(9):2018-26.
Review paper
- Bäckhed, F. (2010) Addressing the gut microbiome and implications for obesity. International Dairy Journal. 20(4): 259-261.
- Caesar, R., Fåk, F., Bäckhed, F. (2010) Gut microbiota effects on obesity and atherosclerosis through modulation of inflammation and lipid metabolism. Journal of Internal Medicine. In Press.
- Bäckhed, F., Crawford, P (2009) Coordinated regulation of the metabolome and lipidome at the host-microbial interface. BBA - Molecular and Cell Biology of Lipids. 1801(3): 240-245.
- Orešič M. Metabolomics, a novel tool for studies of nutrition,
metabolism and lipid dysfunction, Nutr. Metab. Cardiovasc. Dis. 2009;19(11):816-24.
- Orešič M. Systems biology strategy to study lipotoxicity and the metabolic syndrome. Biochim Biophys Acta. 2009. [Epub ahead of print]